6 edition of Chemokines in disease found in the catalog.
Includes bibliographical references and index.
|Statement||edited by Caroline Hébert ; foreword by Peter A. Ward.|
|LC Classifications||QR185.8.C45 C486 1999|
|The Physical Object|
|Pagination||xx, 330 p. :|
|Number of Pages||330|
|LC Control Number||98055169|
The ability of the chemokines to attract specific leukocyte subsets to sites of disease may contribute to the nature and chronicity of the response. For example, in many acute diseases such as bacterial pneumonia and viral or bacterial meningitis, there is a characteristic early, massive influx of neutrophils into the affected host tissue. Chemokines are chemotactic cytokines produced by many kinds of leukocytes and other cell types. They represent a large family of molecules that function to recruit leukocytes to sites of infection and play a role in lymphocyte trafficking by determining which cells will cross the epithelium and where they are directed to .
Chemokines facilitate leukocyte migration and positioning as well as other processes such as angiogenesis and leukocyte degranulation. The burgeoning . Chemokines and Chemokine Receptors: Their Manifold Roles in Homeostasis and Disease Yingying Le1, 2, Ye Zhou1, Pablo Iribarren1 and Ji Ming Wang1, 2 Chemokines are a superfamily of small proteins that bind to G protein-coupled receptors on target cells and.
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled. on Role of chemokines in disease; Lusso, ). On the basis of their pattern of expression, CKs can be classiﬁed as inﬂammatory or homeostatic. Inﬂammatory CKs are induced in productive cells by their injury; their basal expression, which is very low or absent increases when cells are damaged, deﬁning inﬂammatory responses.
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The different Chapters of this book detail the role of different cytokines and chemokines in specific autoimmune disorders. In this Chapter, I highlight the contributions of individual cytokines and chemokines to multiple autoimmune diseases as discussed in detail throughout the book.1–14 The reader is referred to specific Chapters for by: Chemokines and receptors: duets versus symphonies.
The question of chemokine redundancy must be addressed early in any discussion of their potential role in by: Chemokines or chemotactic cytokines are a family of small molecular weight proteins that promote directional migration of leukocytes, endothelial and epithelial cells.
Chemokines are classified into CXC, CC, CX 3 C or C chemokines based on the positioning of the conserved cysteine residues [1, 2].
Based on their function, chemokines can be Cited by: The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines.
Dennis D. Taub, in Encyclopedia of Immunology (Second Edition), Pathological disease states. Many chemokines have been shown to be present in numerous inflammatory and noninflammatory disease states, including sepsis, atherosclerosis, arthritis, cystic fibrosis and asthma.
In many of the inflamed lesions the presence of chemokines is highly correlated with the level of leukocyte. Additional Physical Format: Online version: Chemokines in disease. New York ; Austin: R.G. Landes Co., © (OCoLC) Document Type: Book.
The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments.
Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory : Hardcover. Importantly, each chapter is meant to provide an in-depth review of how cytokines and chemokines participate in each disease, rather than very specific aspects of cytokine or chemokine biology.
The book therefore provides an integrated view of how multiple cytokines and chemokines participate in the initiation and evolution of both systemic and Format: Hardcover. Chemokines and diseases Article Literature Review (PDF Available) in European journal of dermatology: EJD 13(3) May with Reads How we measure 'reads'.
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Purchase Chemokines, Chemokine Receptors and Disease, Volume 55 - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. Edited by Caroline A. Hebert, pp, with illus, Totowa, NJ, Humana Press, In Chemokines in Disease: Biology and Clinical Research, Dr Hébert and a distinguished group of clinical and experimental investigators provide a novel and comprehensive review of chemokines in disease.
The book is organized into 4 main sections, each composed of several well-written : Keith F. Izban. Book Annex Membership Educators Gift Cards Stores & Events Help.
Auto Suggestions are available once you type at least 3 letters. Use up arrow (for mozilla firefox browser alt+up arrow) and down arrow (for mozilla firefox browser alt+down arrow) to review and enter to : $ Given this functional diversity, chemokines have been implicated in a wide variety of pathological states such as infectious disease and cancer, autoimmunity, allergy and transplant rejection [7.
MCP-1 in Human Disease: Insights Gained from Animal Models / Landin Boring, Israel F. Charo and Barrett J. Rollins --pt. Chemokines in Inflammatory Disease.
IL-8 in Animal Models of Disease / Akihisa Harada and Kouji Matsushima. This book examines the role of chemokines in mediating human disease. Specifically, this book presents an overview of the two chemokine supergene families and their receptors. The role of these mediators in arthritis, skin disease and renal disease is evaluated.
Focusing on lung diseases, the Price: $ Chemokines are a family of chemoattractant cytokines (small proteins secreted by cells that influence the immune system) which play a vital role in cell migration through venules from blood into tissue and vice versa, and in the induction of cell movement in response to a chemical (chemokine) gradient by a process known as chemotaxis (Figure 1).In addition, chemokines also regulate lymphoid.
The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory processes.
Chemokines in Disease. Alisa E. Koch, Robert M. Strieter. R.G. Landes Company, - Medical - pages. 0 Reviews. From inside the book. What people are saying - Write a review. We haven't found any reviews in the usual places.
Contents. Chemokine Receptors. The Role of Chemokines in Skin Disease. Chemokines in Arthritis. Chemokine, any of a group of small hormonelike molecules that are secreted by cells and that stimulate the movement of cells of the immune system toward specific sites in the body.
Chemokines are a type of cytokine (a short-lived secreted protein that regulates the function of nearby cells) and may be described more specifically as chemotactic cytokines, because of their ability to cause. In Chemokines: Methods and Protocols, expert researchers provide practical information regarding experimental models and state of the art protocols used to delineate chemokine/chemokine receptor function and their applications in health and disease.Chemokines are capable of heparin binding at their C-terminal end, which enables them to bind to glycosaminoglycan and other negatively charged sugar moieties on cell surfaces and matrix glycoproteins.
This property may result in their adsorption onto endothelial cell lining of the blood vessels, connective tissues and cell matrices.In the Cytokines and Chemokines in Infectious Diseases Handbook, international leaders in the field comprehensively review what is known about the responses of cytokines and chemokines to a variety of human infectious diseases, including gram-negative and gram-positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia.